Mus musculus Gene: Ido2

Summary
InnateDB Gene IDBG-142369.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol Ido2
Gene Name indoleamine 2,3-dioxygenase 2
Synonyms AI265623; C230043N17Rik; Ido-2; Indol1
Species Mus musculus
Ensembl Gene ENSMUSG00000031549
Encoded Proteins
IDBP-142371 indoleamine 2,3-dioxygenase 2
IDBP-401545 indoleamine 2,3-dioxygenase 2
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188676:
Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8: 24531892-24576333
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000033953  ENSMUSP00000033953
ENSMUST00000121992  ENSMUSP00000113979
ENSMUST00000140417 
ENSMUST00000138335 
ENSMUST00000138155 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
 
Gene Ontology
Accession GO Term
Molecular Function
GO:0004833 tryptophan 2,3-dioxygenase activity
GO:0020037 heme binding
GO:0033754 indoleamine 2,3-dioxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0019441 tryptophan catabolic process to kynurenine
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSG00000188676 Ortholuge SSD Ortholog Ortholog supports species divergence
ENSBTAG00000005725 Not yet available Ortholuge SSD Ortholog Ortholog supports species divergence
Pathways
NETPATH
REACTOME
REACT_90199 Tryptophan catabolism
KEGG
mmu05143  African trypanosomiasis
mmu01100  Metabolic pathways
mmu00380  Tryptophan metabolism
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_916 Tryptophan catabolism
KEGG
hsa05143  African trypanosomiasis
hsa01100  Metabolic pathways
hsa00380  Tryptophan metabolism
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8R0V5 
TrEMBL A4UHF3 B1AC39
UniProt Splice Variant
Entrez Gene 209176 
UniGene Mm.219580 Mm.398187
RefSeq NM_145949 
OMIM
CCDS CCDS40298 
HPRD
IMGT
MGI ID MGI:2142489 
MGI Symbol Ido2
EMBL AC114602 BC026393 CH466580 EF137182 EU440733
GenPept AAH26393  ABO33433  ACA25598  EDL32857 
ImmGen Ido2 (murine) 
RNA Seq Atlas 209176