Mus musculus Gene: Xpnpep2
Summary
InnateDB Gene IDBG-142723.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpnpep2
Gene Name X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037005
Encoded Proteins
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122121:
Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. [provided by RefSeq, Jul 2008]
Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the \'pita bread fold\' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:48108725-48136981
Strand Forward strand
Band A5
Transcripts
ENSMUST00000077775 ENSMUSP00000076951
ENSMUST00000115000 ENSMUSP00000110652
ENSMUST00000114998 ENSMUSP00000110650
ENSMUST00000129677
ENSMUST00000156654
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004177 aminopeptidase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Protein digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL B1AVD1 B1AVD2 Q8BU59
UniProt Splice Variant
Entrez Gene 170745
UniGene Mm.129279
RefSeq NM_001289729 NM_133213 XM_006541431 XM_006541432
OMIM
CCDS CCDS30106
HPRD
IMGT
MGI ID MGI:2180001
MGI Symbol Xpnpep2
EMBL AK087627 AL672274 CH466570
GenPept BAC39947 EDL29066
RNA Seq Atlas 170745