Version 5.4
Mus musculus Gene: Pou4f3
Summary
InnateDB Gene IDBG-143219.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pou4f3
Gene Name POU domain, class 4, transcription factor 3
Synonyms Brn3.1; Brn3c; ddl; dreidel
Species Mus musculus
Ensembl Gene ENSMUSG00000024497
Encoded Proteins
IDBP-143221
POU domain, class 4, transcription factor 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000091010:
This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:42394539-42397249
Strand Forward strand
Band B3
Transcripts
ENSMUST00000025374 ENSMUSP00000025374
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007605 sensory perception of sound
GO:0021562 vestibulocochlear nerve development
GO:0031290 retinal ganglion cell axon guidance
GO:0042472 inner ear morphogenesis
GO:0042491 auditory receptor cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048675 axon extension
GO:0048839 inner ear development
GO:0050885 neuromuscular process controlling balance
GO:0051402 neuron apoptotic process
GO:0060113 inner ear receptor cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000091010
View Gene Order
ENSBTAG00000018817
Not yet available
Cross-References
SwissProt Q63955
TrEMBL
UniProt Splice Variant
Entrez Gene 18998
UniGene Mm.221181 Mm.488204
RefSeq NM_138945
OMIM
CCDS CCDS29212
HPRD
IMGT
MGI ID MGI:102523
MGI Symbol Pou4f3
EMBL BC145941 CH466528 S69352
GenPept AAB30579 AAI45942 EDL10035
RNA Seq Atlas 18998

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca