Version 5.4
Mus musculus Gene: B3gnt5
Summary
InnateDB Gene IDBG-143290.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3gnt5
Gene Name UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Synonyms beta3GnT5
Species Mus musculus
Ensembl Gene ENSMUSG00000022686
Encoded Proteins
IDBP-143292
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
IDBP-401494
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
IDBP-401493
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
IDBP-625844
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176597:
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:19760208-19772753
Strand Forward strand
Band A3
Transcripts
ENSMUST00000079780 ENSMUSP00000078712
ENSMUST00000121344 ENSMUSP00000112624
ENSMUST00000119468 ENSMUSP00000113145
ENSMUST00000152845
ENSMUST00000131557
ENSMUST00000155780
ENSMUST00000164397 ENSMUSP00000126157
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity
GO:0008917 lipopolysaccharide N-acetylglucosaminyltransferase activity
GO:0047256 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0007417 central nervous system development
GO:0030148 sphingolipid biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005622 intracellular
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000176597
View Gene Order
ENSBTAG00000010397
Not yet available
Pathways
NETPATH
REACTOME
REACT_198517
O-linked glycosylation of mucins pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_204003
O-linked glycosylation pathway
KEGG
mmu00601
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115606
O-linked glycosylation of mucins pathway
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00601
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q8BGY6
TrEMBL
UniProt Splice Variant
Entrez Gene 108105
UniGene Mm.33935
RefSeq NM_001159408 NM_001159407 NM_054052 XM_006521707
OMIM
CCDS CCDS28040
HPRD
IMGT
MGI ID MGI:2137302
MGI Symbol B3gnt5
EMBL AB059620 AK032911 AK048010 AK083839 AY029203 BC063076
GenPept AAH63076 AAK31579 BAC28082 BAC33213 BAC39037 BAC66698
RNA Seq Atlas 108105

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca