InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Nelf

Summary

InnateDB Gene

IDBG-143801.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nelf

Gene Name

nasal embryonic LHRH factor

Synonyms

Jacob; Nelf

Species

Mus musculus

Ensembl Gene

ENSMUSG00000006476

Encoded Proteins

IDBP-143803

nasal embryonic LHRH factor

IDBP-143805

nasal embryonic LHRH factor

IDBP-143807

nasal embryonic LHRH factor

IDBP-143809

nasal embryonic LHRH factor

IDBP-251854

nasal embryonic LHRH factor

IDBP-251856

nasal embryonic LHRH factor

IDBP-273787

nasal embryonic LHRH factor

IDBP-538426

nasal embryonic LHRH factor

IDBP-537193

nasal embryonic LHRH factor

IDBP-533872

nasal embryonic LHRH factor

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165802:
The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:25054355-25062881

Strand

Forward strand

Band

Transcripts

ENSMUST00000100334	ENSMUSP00000097908
ENSMUST00000074422	ENSMUSP00000074022
ENSMUST00000006646	ENSMUSP00000006646
ENSMUST00000102931	ENSMUSP00000099995
ENSMUST00000114388	ENSMUSP00000110030
ENSMUST00000114386	ENSMUSP00000110028
ENSMUST00000116574	ENSMUSP00000112273
ENSMUST00000152122	ENSMUSP00000121580
ENSMUST00000141866
ENSMUST00000155909
ENSMUST00000132172	ENSMUSP00000116106
ENSMUST00000140737
ENSMUST00000144520
ENSMUST00000135328
ENSMUST00000134744	ENSMUSP00000120376
ENSMUST00000140733
ENSMUST00000152506
ENSMUST00000124309

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	1 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0035307	positive regulation of protein dephosphorylation
GO:0043523	regulation of neuron apoptotic process
GO:0048168	regulation of neuronal synaptic plasticity
GO:0048814	regulation of dendrite morphogenesis
GO:0071230	cellular response to amino acid stimulus
GO:0071257	cellular response to electrical stimulus
GO:0071371	cellular response to gonadotropin stimulus
GO:2001224	positive regulation of neuron migration

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005719	nuclear euchromatin
GO:0005737	cytoplasm
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0016363	nuclear matrix
GO:0030054	cell junction
GO:0030425	dendrite
GO:0030863	cortical cytoskeleton
GO:0031965	nuclear membrane
GO:0043005	neuron projection
GO:0043204	perikaryon
GO:0045202	synapse
GO:0045211	postsynaptic membrane
GO:0097440	apical dendrite

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000165802

View Gene Order

ENSBTAG00000030247

Not yet available

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.418413 Mm.42956 Mm.443955

RefSeq

NM_001039386 NM_001039387 NM_001177654 NM_001177655 NM_020276 XM_006498200 XM_006498201 XM_006498202 XM_006498203

OMIM

CCDS

CCDS15745 CCDS15746 CCDS15747 CCDS50523

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas