Version 5.4
Homo sapiens Gene: GOLPH3
Summary
InnateDB Gene IDBG-14459.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOLPH3
Gene Name golgi phosphoprotein 3 (coat-protein)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000113384
Encoded Proteins
IDBP-14461
golgi phosphoprotein 3 (coat-protein)
IDBP-483295
golgi phosphoprotein 3 (coat-protein)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:32124704-32174350
Strand Reverse strand
Band p13.3
Transcripts
ENST00000265070 ENSP00000265070
ENST00000503610 ENSP00000426752
ENST00000512668
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0070273 phosphatidylinositol-4-phosphate binding
Biological Process
GO:0007030 Golgi organization
GO:0008283 cell proliferation
GO:0009101 glycoprotein biosynthetic process
GO:0009306 protein secretion
GO:0010467 gene expression
GO:0010821 regulation of mitochondrion organization
GO:0016477 cell migration
GO:0030032 lamellipodium assembly
GO:0032008 positive regulation of TOR signaling
GO:0043001 Golgi to plasma membrane protein transport
GO:0045053 protein retention in Golgi apparatus
GO:0048194 Golgi vesicle budding
GO:0050714 positive regulation of protein secretion
GO:0050901 leukocyte tethering or rolling
GO:0060352 cell adhesion molecule production
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0031985 Golgi cisterna
GO:0032580 Golgi cisterna membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022200
View Gene Order
ENSBTAG00000032848
Not yet available
Cross-References
SwissProt
TrEMBL D6REM1
UniProt Splice Variant
Entrez Gene 64083
UniGene Hs.408909 Hs.598403 Hs.707194
RefSeq NM_022130
HUGO HGNC:15452
OMIM 612207
CCDS CCDS3896
HPRD 11007
IMGT
EMBL AC022444 AC025178 AC025181
GenPept
RNA Seq Atlas 64083

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca