Version 5.4
Mus musculus Gene: Tdrd7
Summary
InnateDB Gene IDBG-144670.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tdrd7
Gene Name tudor domain containing 7
Synonyms 5730495N10Rik; AI447470; PCTAIRE2BP
Species Mus musculus
Ensembl Gene ENSMUSG00000035517
Encoded Proteins
IDBP-144672
tudor domain containing 7
IDBP-265955
tudor domain containing 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196116:
This gene encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs. Mutation in this gene has been associated with pediatric cataracts. Mutation of the similar gene in mice has been associated with cataracts, glaucoma and a block in spermatogenesis. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:45965334-46034761
Strand Forward strand
Band B1
Transcripts
ENSMUST00000102929 ENSMUSP00000099993
ENSMUST00000107777 ENSMUSP00000103406
ENSMUST00000151422
ENSMUST00000140270
ENSMUST00000155936
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0002089 lens morphogenesis in camera-type eye
GO:0007281 germ cell development
GO:0007283 spermatogenesis
GO:0010608 posttranscriptional regulation of gene expression
GO:0070306 lens fiber cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0005759 mitochondrial matrix
GO:0030529 ribonucleoprotein complex
GO:0033391 chromatoid body
GO:0035770 ribonucleoprotein granule
GO:0043186 P granule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196116
View Gene Order
ENSBTAG00000003719
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
aurora_a_pathway
Aurora A signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.275413 Mm.408113
RefSeq NM_001290475 NM_146142 XM_006537516 XM_006537517
OMIM
CCDS CCDS18142 CCDS71381
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca