Version 5.4
Mus musculus Gene: Atp5s
Summary
InnateDB Gene IDBG-144742.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp5s
Gene Name ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
Synonyms 1110015E18Rik; ATPW
Species Mus musculus
Ensembl Gene ENSMUSG00000054894
Encoded Proteins
IDBP-144744
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125375:
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:69724962-69744658
Strand Forward strand
Band C2
Transcripts
ENSMUST00000021372 ENSMUSP00000021372
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015992 proton transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125375
View Gene Order
ENSBTAG00000015202
Not yet available
Pathways
NETPATH
REACTOME
REACT_189162
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_188937
Metabolism pathway
REACT_261922
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_245290
Formation of ATP by chemiosmotic coupling pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_6759
Formation of ATP by chemiosmotic coupling pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
REACT_212639
Formation of ATP by chemiosmotic coupling pathway
REACT_215469
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_218878
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9CRA7
TrEMBL
UniProt Splice Variant
Entrez Gene 68055
UniGene Mm.27844 Mm.399317 Mm.473206
RefSeq NM_026536 XM_006516182 XM_006516184
OMIM
CCDS CCDS25954
HPRD
IMGT
MGI ID MGI:1915305
MGI Symbol Atp5s
EMBL AK003725 AK009141 BC027442
GenPept AAH27442 BAB22960
RNA Seq Atlas 68055

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca