Version 5.4
| Homo sapiens Gene: ATP5S | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-5967.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | ATP5S | ||||||||||||||||||
| Gene Name | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000125375 | ||||||||||||||||||
| Encoded Proteins |
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 14:50312326-50335558 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q21.3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Formation of ATP by chemiosmotic coupling pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | Q99766 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 27109 | ||||||||||||||||||
| UniGene | Hs.656689 | ||||||||||||||||||
| RefSeq | NM_015684 NM_001003803 NM_001003805 XM_005267537 XM_005267539 | ||||||||||||||||||
| HUGO | HGNC:18799 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS45102 CCDS32075 CCDS32076 | ||||||||||||||||||
| HPRD | 12503 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AK290008 AL359397 AY052377 BC011549 CH471078 U79253 | ||||||||||||||||||
| GenPept | AAB50202 AAH11549 AAL13058 BAF82697 EAW65718 EAW65722 | ||||||||||||||||||
| RNA Seq Atlas | 27109 | ||||||||||||||||||