Version 5.4
Mus musculus Gene: Sema4c
Summary
InnateDB Gene IDBG-144779.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sema4c
Gene Name sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Synonyms AI426163; mKIAA1739; Semacl1; Semaf; Semai
Species Mus musculus
Ensembl Gene ENSMUSG00000026121
Encoded Proteins
IDBP-250638
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168758:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:36548642-36558381
Strand Reverse strand
Band B
Transcripts
ENSMUST00000114991 ENSMUSP00000110643
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0001843 neural tube closure
GO:0007275 multicellular organismal development
GO:0021535 cell migration in hindbrain
GO:0021549 cerebellum development
GO:0032874 positive regulation of stress-activated MAPK cascade
GO:0042692 muscle cell differentiation
GO:0071526 semaphorin-plexin signaling pathway
Cellular Component
GO:0005615 extracellular space
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168758
View Gene Order
ENSBTAG00000021920
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt Q64151
TrEMBL D3YYA8
UniProt Splice Variant
Entrez Gene 20353
UniGene Mm.29558
RefSeq NM_001126047 XM_006495803 XM_006495804 XM_006495805 XM_006495806 XM_006495807 XM_006495808 XM_006495809 XM_006495810
OMIM
CCDS CCDS48240
HPRD
IMGT
MGI ID MGI:109252
MGI Symbol Sema4c
EMBL AC084391 S79463
GenPept AAB35184
RNA Seq Atlas 20353

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca