Version 5.4
Mus musculus Gene: Vps37c
Summary
InnateDB Gene IDBG-144868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps37c
Gene Name vacuolar protein sorting 37C (yeast)
Synonyms 5730409F24Rik; AU042646
Species Mus musculus
Ensembl Gene ENSMUSG00000048832
Encoded Proteins
IDBP-144870
vacuolar protein sorting 37C (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167987:
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:10688815-10714419
Strand Forward strand
Band A
Transcripts
ENSMUST00000087951 ENSMUSP00000085264
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0000813 ESCRT I complex
GO:0005634 nucleus
GO:0031902 late endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000167987
View Gene Order
ENSBTAG00000008064
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_198518
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115893
Membrane binding and targetting of GAG proteins pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_27258
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
REACT_115860
Synthesis And Processing Of GAG, GAGPOL Polyproteins pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_6818
Assembly Of The HIV Virion pathway
REACT_6359
Budding and maturation of HIV virion pathway
REACT_116125
Disease pathway
REACT_11123
Membrane Trafficking pathway
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt Q8R105
TrEMBL
UniProt Splice Variant
Entrez Gene 107305
UniGene Mm.19091
RefSeq NM_181403 XM_006526572 XM_006526573 XM_006526574 XM_006526575
OMIM
CCDS CCDS29585
HPRD
IMGT
MGI ID MGI:2147661
MGI Symbol Vps37c
EMBL AK158833 AK159309 BC025865
GenPept AAH25865 BAE34687 BAE34977
RNA Seq Atlas 107305

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca