Version 5.4
Mus musculus Gene: Trim36
Summary
InnateDB Gene IDBG-145013.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trim36
Gene Name tripartite motif-containing 36
Synonyms D18Wsu100e; haprin
Species Mus musculus
Ensembl Gene ENSMUSG00000033949
Encoded Proteins
IDBP-145015
tripartite motif-containing 36
IDBP-622569
tripartite motif-containing 36
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 23438823
[Homo sapiens] TRIM36 was identified in a systematic screen for positive regulators of innate immune responses.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152503:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:46165302-46212607
Strand Reverse strand
Band C
Transcripts
ENSMUST00000037011 ENSMUSP00000037978
ENSMUST00000167364 ENSMUSP00000129771
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0007340 acrosome reaction
GO:0016567 protein ubiquitination
GO:0051726 regulation of cell cycle
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005622 intracellular
GO:0005856 cytoskeleton
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000152503
View Gene Order
ENSBTAG00000014027
Not yet available
Pathways
NETPATH
REACTOME
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_230745
Immune System pathway
REACT_199115
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9Q3A0
UniProt Splice Variant
Entrez Gene 28105
UniGene Mm.277382 Mm.413325 Mm.475061
RefSeq NM_001170855 NM_178872
OMIM
CCDS CCDS50279 CCDS29229
HPRD
IMGT
MGI ID MGI:106264
MGI Symbol Trim36
EMBL AC124717
GenPept
RNA Seq Atlas 28105

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca