Version 5.4
Mus musculus Gene: Acad8
Summary
InnateDB Gene IDBG-145450.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acad8
Gene Name acyl-Coenzyme A dehydrogenase family, member 8
Synonyms 2310016C19Rik; AI786953
Species Mus musculus
Ensembl Gene ENSMUSG00000031969
Encoded Proteins
IDBP-145452
acyl-Coenzyme A dehydrogenase family, member 8
IDBP-401513
acyl-Coenzyme A dehydrogenase family, member 8
IDBP-533457
acyl-Coenzyme A dehydrogenase family, member 8
IDBP-542194
acyl-Coenzyme A dehydrogenase family, member 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151498:
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.[provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:26974135-26999566
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000060513 ENSMUSP00000054370
ENSMUST00000120367 ENSMUSP00000112908
ENSMUST00000129490
ENSMUST00000151075
ENSMUST00000128923 ENSMUSP00000122444
ENSMUST00000132293 ENSMUSP00000123012
ENSMUST00000138102
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006574 valine catabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000151498
View Gene Order
ENSBTAG00000012937
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_254568
Branched-chain amino acid catabolism pathway
KEGG
mmu00280
Valine, leucine and isoleucine degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_197
Branched-chain amino acid catabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
KEGG
hsa00280
Valine, leucine and isoleucine degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.289244
RefSeq NM_025862 XM_006510548 XM_006510549
OMIM
CCDS CCDS40567
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca