InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cdk19

Summary

InnateDB Gene

IDBG-145470.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cdk19

Gene Name

cyclin-dependent kinase 19

Synonyms

2700084L06Rik; AI845279; AW228747; Cdc2l6; CDK11; mKIAA1028

Species

Mus musculus

Ensembl Gene

ENSMUSG00000038481

Encoded Proteins

IDBP-145472

cyclin-dependent kinase 19

IDBP-145476

cyclin-dependent kinase 19

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155111:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. [provided by RefSeq, Jul 2008]
This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:40349308-40483818

Strand

Forward strand

Band

Transcripts

ENSMUST00000044672	ENSMUSP00000040936
ENSMUST00000095743	ENSMUSP00000093414

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004693	cyclin-dependent protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups