Bos taurus Gene: CDK19
Summary
InnateDB Gene IDBG-631527.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDK19
Gene Name cyclin-dependent kinase 19
Synonyms CDC2L6; CDK8
Species Bos taurus
Ensembl Gene ENSBTAG00000007288
Encoded Proteins
cyclin-dependent kinase 19
cyclin-dependent kinase 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155111:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. [provided by RefSeq, Jul 2008]
This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:40072435-40122499
Strand Forward strand
Band
Transcripts
ENSBTAT00000063412 ENSBTAP00000055711
ENSBTAT00000009583 ENSBTAP00000009583
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Transcriptional regulation of white adipocyte differentiation pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Transcriptional regulation of white adipocyte differentiation pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
PPARA activates gene expression pathway
Developmental Biology pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3N1G7
UniProt Splice Variant
Entrez Gene 511802
UniGene Bt.92782
RefSeq NM_001205707 XM_005210778 XM_005210779 XM_005210780
HUGO HGNC:19338
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02025901 DAAA02025902 DAAA02025903
GenPept
RNA Seq Atlas 511802