Mus musculus Gene: Gpr44 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-145608.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Gpr44 | ||||||||||
Gene Name | G protein-coupled receptor 44 | ||||||||||
Synonyms | Crth2; Gpr44; Grp45 | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Gene | ENSMUSG00000034117 | ||||||||||
Encoded Proteins |
G protein-coupled receptor 44
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183134:
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011] This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3\' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 19:10937160-10942511 | ||||||||||
Strand | Forward strand | ||||||||||
Band | A | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME |
GPCR downstream signaling pathway
Prostanoid ligand receptors pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
Eicosanoid ligand-binding receptors pathway
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KEGG | |||||||||||
INOH | |||||||||||
PID NCI | |||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
G alpha (i) signalling events pathway
Prostanoid ligand receptors pathway
Eicosanoid ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
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KEGG | |||||||||||
INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | Q9Z2J6 | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 14764 | ||||||||||
UniGene | Mm.470721 | ||||||||||
RefSeq | NM_009962 XM_006526695 XM_006526696 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS29592 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
MGI ID | MGI:1330275 | ||||||||||
MGI Symbol | Ptgdr2 | ||||||||||
EMBL | AB109091 AB109092 AF054507 BC111906 CH466534 | ||||||||||
GenPept | AAD13525 AAI11907 BAC81436 BAC81437 EDL41395 | ||||||||||
RNA Seq Atlas | 14764 | ||||||||||