Version 5.4
Mus musculus Gene: Bbc3
Summary
InnateDB Gene IDBG-146380.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bbc3
Gene Name BCL2 binding component 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000002083
Encoded Proteins
IDBP-146382
BCL2 binding component 3
IDBP-538290
BCL2 binding component 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:16309616-16318205
Strand Forward strand
Band A2
Transcripts
ENSMUST00000002152 ENSMUSP00000002152
ENSMUST00000136781 ENSMUSP00000119225
ENSMUST00000147267
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001836 release of cytochrome c from mitochondria
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008340 determination of adult lifespan
GO:0030308 negative regulation of cell growth
GO:0034976 response to endoplasmic reticulum stress
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043065 positive regulation of apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0045926 negative regulation of growth
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070245 positive regulation of thymocyte apoptotic process
GO:0071479 cellular response to ionizing radiation
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097190 apoptotic signaling pathway
GO:0097194 execution phase of apoptosis
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:2001056 positive regulation of cysteine-type endopeptidase activity
Cellular Component
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04115
p53 signaling pathway pathway
mmu05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.7660
RefSeq NM_133234 XM_006539575 XM_006539577 XM_006539578 XM_006539579 XM_006539580 XM_006539581 XM_006539582
OMIM
CCDS CCDS20847
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca