Version 5.4
| Mus musculus Gene: Adamts8 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-146397.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Adamts8 | ||||||||
| Gene Name | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 | ||||||||
| Synonyms | METH-2; METH2 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000031994 | ||||||||
| Encoded Proteins |
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134917:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 9:30942562-30963838 | ||||||||
| Strand | Forward strand | ||||||||
| Band | A4 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Post-translational protein modification pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Mm.100582 Mm.403039 | ||||||||
| RefSeq | NM_013906 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS22946 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | |||||||||
| MGI Symbol | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||