Version 5.4
Mus musculus Protein: Adamts8
Summary
InnateDB Protein IDBP-146399.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adamts8
Protein Name a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
Synonyms METH-2; METH2;
Species Mus musculus
Ensembl Protein ENSMUSP00000069644
InnateDB Gene IDBG-146397 (Adamts8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID MGI:1353468
InterPro IPR000884 Thrombospondin, type 1 repeat
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
IPR010294 ADAM-TS Spacer 1
IPR013273 Peptidase M12B, ADAM-TS
IPR013277 Peptidase M12B, ADAM-TS8
PFAM PF00090
PF01421
PF01562
PF08516
PF05986
PRINTS PR01857
PR01861
PIRSF
SMART SM00209
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q99JP1
UniProt Splice Variant
Entrez Gene 30806
UniGene Mm.403039
RefSeq NP_038934
MGI ID
MGI Symbol Adamts8
OMIM
CCDS CCDS22946
HPRD
IMGT
EMBL BC005780 CT025653
GenPept AAH05780

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca