Mus musculus Gene: Eci1
Summary
InnateDB Gene IDBG-146474.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eci1
Gene Name enoyl-Coenzyme A delta isomerase 1
Synonyms Dci; eci
Species Mus musculus
Ensembl Gene ENSMUSG00000024132
Encoded Proteins
enoyl-Coenzyme A delta isomerase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167969:
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:24426683-24439316
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000024946 ENSMUSP00000024946
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004165 dodecenoyl-CoA delta-isomerase activity
Biological Process
GO:0006635 fatty acid beta-oxidation
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Mitochondrial Fatty Acid Beta-Oxidation pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids pathway
KEGG
Fatty acid degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Mitochondrial Fatty Acid Beta-Oxidation pathway
Metabolism pathway
KEGG
Fatty acid degradation pathway
INOH
PID NCI
Cross-References
SwissProt P42125
TrEMBL
UniProt Splice Variant
Entrez Gene 13177
UniGene
RefSeq NM_010023
OMIM
CCDS CCDS28480
HPRD
IMGT
MGI ID MGI:94871
MGI Symbol Eci1
EMBL AC154237 AK029481 BC022712 BC054444 CH466606 Z14049 Z14050 Z14051 Z14052 Z14053 Z14054
GenPept AAH22712 AAH54444 BAC26469 CAA78417 CAA78418 EDL22317
RNA Seq Atlas 13177