Version 5.4
Homo sapiens Gene: SCARA5
Summary
InnateDB Gene IDBG-14672.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCARA5
Gene Name scavenger receptor class A, member 5 (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168079
Encoded Proteins
IDBP-14674
scavenger receptor class A, member 5 (putative)
IDBP-14676
scavenger receptor class A, member 5 (putative)
IDBP-482040
scavenger receptor class A, member 5 (putative)
IDBP-475770
scavenger receptor class A, member 5 (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:27869882-27992727
Strand Reverse strand
Band p21.1
Transcripts
ENST00000354914 ENSP00000346990
ENST00000380385 ENSP00000369746
ENST00000524352 ENSP00000428663
ENST00000518030 ENSP00000430713
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
GO:0070287 ferritin receptor activity
Biological Process
GO:0006879 cellular iron ion homeostasis
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0010468 regulation of gene expression
GO:0030193 regulation of blood coagulation
GO:0034605 cellular response to heat
GO:0034755 iron ion transmembrane transport
GO:0070207 protein homotrimerization
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022032
View Gene Order
ENSBTAG00000019636
Not yet available
Pathways
NETPATH
REACTOME
REACT_160300
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_163699
Scavenging by Class A Receptors pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6ZMJ2
TrEMBL
UniProt Splice Variant
Entrez Gene 286133
UniGene Hs.591833
RefSeq NM_173833
HUGO HGNC:28701
OMIM 611306
CCDS CCDS6064
HPRD
IMGT
EMBL AK172746 AY337579 AY358150 BC033153
GenPept AAH33153 AAQ17470 AAQ88517 BAD18733
RNA Seq Atlas 286133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca