Version 5.4
| Mus musculus Gene: Smpd2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-146756.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Smpd2 | ||||||||
| Gene Name | sphingomyelin phosphodiesterase 2, neutral | ||||||||
| Synonyms | AW108287; nSMase; nSMase1 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000019822 | ||||||||
| Encoded Proteins |
sphingomyelin phosphodiesterase 2, neutral
sphingomyelin phosphodiesterase 2, neutral
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene encodes a protein with similarity to the human nSMase1 protein. In humans, the nSMase1 protein was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 10:41485642-41490369 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | B2 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Glycosphingolipid metabolism pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Ceramide signalling pathway
Signalling by NGF pathway
Signal Transduction pathway
p75 NTR receptor-mediated signalling pathway
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| KEGG |
Sphingolipid metabolism pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Ceramide signalling pathway
Glycosphingolipid metabolism pathway
Sphingolipid metabolism pathway
Signalling by NGF pathway
Metabolism of lipids and lipoproteins pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
Metabolism pathway
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| KEGG |
Sphingolipid metabolism pathway
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| INOH | |||||||||
| PID NCI |
TNF receptor signaling pathway
p75(NTR)-mediated signaling
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Mm.452529 | ||||||||
| RefSeq | NM_009213 XM_006512633 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS23805 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | |||||||||
| MGI Symbol | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||