Version 5.4
Mus musculus Gene: Dfna5
Summary
InnateDB Gene IDBG-146820.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dfna5
Gene Name deafness, autosomal dominant 5 (human)
Synonyms 2310037D07Rik; 4932441K13Rik; Dfna5h; EG14210; Fin15
Species Mus musculus
Ensembl Gene ENSMUSG00000029821
Encoded Proteins
IDBP-146808
deafness, autosomal dominant 5 (human)
IDBP-146822
deafness, autosomal dominant 5 (human)
IDBP-627582
deafness, autosomal dominant 5 (human)
IDBP-627585
deafness, autosomal dominant 5 (human)
IDBP-627587
deafness, autosomal dominant 5 (human)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105928:
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:50189369-50263862
Strand Reverse strand
Band B2.3
Transcripts
ENSMUST00000101405 ENSMUSP00000098952
ENSMUST00000031845 ENSMUSP00000031845
ENSMUST00000165099 ENSMUSP00000130522
ENSMUST00000167893 ENSMUSP00000132062
ENSMUST00000170142 ENSMUSP00000126759
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
GO:0007605 sensory perception of sound
GO:0008285 negative regulation of cell proliferation
GO:0060113 inner ear receptor cell differentiation
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000105928
View Gene Order
ENSBTAG00000015326
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.248361 Mm.408137 Mm.461943 Mm.463873 Mm.489121
RefSeq NM_018769 XM_006506401
OMIM
CCDS CCDS20130
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca