Version 5.4
Bos taurus Gene: DFNA5
Summary
InnateDB Gene IDBG-633688.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DFNA5
Gene Name non-syndromic hearing impairment protein 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015326
Encoded Proteins
IDBP-685418
deafness, autosomal dominant 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105928:
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:71540350-71614456
Strand Forward strand
Band
Transcripts
ENSBTAT00000020371 ENSBTAP00000020371
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008285 negative regulation of cell proliferation
GO:0060113 inner ear receptor cell differentiation
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000105928
View Gene Order
ENSMUSG00000029821
View Gene Order
Cross-References
SwissProt
TrEMBL E1BFC3
UniProt Splice Variant
Entrez Gene 616398
UniGene Bt.44669
RefSeq NM_001193112
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010994
GenPept
RNA Seq Atlas 616398

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca