Mus musculus Gene: Zfp189
Summary
InnateDB Gene IDBG-147022.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp189
Gene Name zinc finger protein 189
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039634
Encoded Proteins
zinc finger protein 189
zinc finger protein 189
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136870:
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30%% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:49521176-49531517
Strand Forward strand
Band B1
Transcripts
ENSMUST00000042964 ENSMUSP00000036663
ENSMUST00000107696 ENSMUSP00000103324
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Generic Transcription Pathway pathway
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q8BKP2
UniProt Splice Variant
Entrez Gene 230162
UniGene Mm.186994
RefSeq NM_001289901 XM_006537846 NM_145547 XM_006537845
OMIM
CCDS CCDS18175
HPRD
IMGT
MGI ID MGI:2444707
MGI Symbol Zfp189
EMBL AK051265 AL772310 BC087833 CH466565
GenPept AAH87833 BAC34582 EDL02317
RNA Seq Atlas 230162