Version 5.4
| Homo sapiens Gene: ZNF189 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-78941.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | ZNF189 | ||||||||||||||||||
| Gene Name | zinc finger protein 189 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000136870 | ||||||||||||||||||
| Encoded Proteins |
zinc finger protein 189
zinc finger protein 189
zinc finger protein 189
zinc finger protein 189
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010] Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30%% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 9:101398873-101410660 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q31.1 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Generic Transcription Pathway pathway
Gene Expression pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | O75820 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 7743 | ||||||||||||||||||
| UniGene | Hs.50123 | ||||||||||||||||||
| RefSeq | NM_197977 XM_006717280 XM_006717281 NM_001278231 NM_001278232 NM_001278240 NM_003452 | ||||||||||||||||||
| HUGO | HGNC:12980 | ||||||||||||||||||
| OMIM | 603132 | ||||||||||||||||||
| CCDS | CCDS6755 CCDS65096 CCDS6754 CCDS75867 | ||||||||||||||||||
| HPRD | 11930 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AF025770 AF025771 AF025772 AK290163 AL353621 BC092425 BC126120 BC143876 CH471105 U75454 U95991 U95992 | ||||||||||||||||||
| GenPept | AAC25909 AAC25910 AAC39798 AAC39799 AAC39800 AAD50527 AAD50528 AAH92425 AAI26121 AAI43877 BAF82852 CAI14611 CAI14612 CAI14613 EAW58949 | ||||||||||||||||||
| RNA Seq Atlas | 7743 | ||||||||||||||||||