Version 5.4
Mus musculus Gene: Gpr112
Summary
InnateDB Gene IDBG-147165.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr112
Gene Name G protein-coupled receptor 112
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053852
Encoded Proteins
IDBP-147182
G protein-coupled receptor 112
IDBP-532191
G protein-coupled receptor 112
IDBP-538377
G protein-coupled receptor 112
IDBP-540601
G protein-coupled receptor 112
IDBP-540379
G protein-coupled receptor 112
IDBP-625222
G protein-coupled receptor 112
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156920:
This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:56870163-57001558
Strand Forward strand
Band A6
Transcripts
ENSMUST00000096431 ENSMUSP00000094165
ENSMUST00000154818 ENSMUSP00000119486
ENSMUST00000153784 ENSMUSP00000116634
ENSMUST00000136396 ENSMUSP00000116655
ENSMUST00000145035 ENSMUSP00000122908
ENSMUST00000168724 ENSMUSP00000127627
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000156920
View Gene Order
Cross-References
SwissProt B7ZCC9
TrEMBL Q3UNS7 Q80T58
UniProt Splice Variant
Entrez Gene 236798
UniGene Mm.35282
RefSeq XM_003085259
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:2685213
MGI Symbol Gpr112
EMBL AK144045 AL671998 AL672263 AY255580 BC132476 BC132480 CH466583
GenPept AAI32477 AAI32481 AAO85092 BAE25670 CAX16065 CAX16066 CAX16092 CAX16093 EDL42159
RNA Seq Atlas 236798

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca