Version 5.4
Mus musculus Gene: Grin3a
Summary
InnateDB Gene IDBG-147227.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Grin3a
Gene Name glutamate receptor ionotropic, NMDA3A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039579
Encoded Proteins
IDBP-147229
glutamate receptor ionotropic, NMDA3A
IDBP-147231
glutamate receptor ionotropic, NMDA3A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198785:
This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:49661611-49845744
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000076674 ENSMUSP00000075970
ENSMUST00000093859 ENSMUSP00000091381
ENSMUST00000149059
ENSMUST00000131797
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004970 ionotropic glutamate receptor activity
GO:0004972 N-methyl-D-aspartate selective glutamate receptor activity
GO:0005215 transporter activity
GO:0005234 extracellular-glutamate-gated ion channel activity
GO:0005262 calcium channel activity
GO:0005515 protein binding
GO:0016594 glycine binding
GO:0042165 neurotransmitter binding
GO:0042802 identical protein binding
GO:0051721 protein phosphatase 2A binding
Biological Process
GO:0006810 transport
GO:0006816 calcium ion transport
GO:0016358 dendrite development
GO:0034220 ion transmembrane transport
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035249 synaptic transmission, glutamatergic
GO:0045471 response to ethanol
GO:0048511 rhythmic process
GO:0060134 prepulse inhibition
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0017146 N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 cell junction
GO:0030425 dendrite
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0045202 synapse
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198785
View Gene Order
ENSBTAG00000018445
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.440095 Mm.482499
RefSeq NM_001033351 NM_001276355 XM_006537913
OMIM
CCDS CCDS51175 CCDS71385
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca