Version 5.4
Homo sapiens Gene: PLK5
Summary
InnateDB Gene IDBG-14733.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLK5
Gene Name polo-like kinase 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185988
Encoded Proteins
IDBP-760853
IDBP-763208
IDBP-765766
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1524074-1535456
Strand Forward strand
Band p13.3
Transcripts
ENST00000334770 ENSP00000466248
ENST00000454744 ENSP00000468376
ENST00000588430 ENSP00000465896
ENST00000588292
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0002357 defense response to tumor cell
GO:0006468 protein phosphorylation
GO:0006927 transformed cell apoptotic process
GO:0007067 mitotic nuclear division
GO:0010976 positive regulation of neuron projection development
GO:0031572 G2 DNA damage checkpoint
GO:0071363 cellular response to growth factor stimulus
GO:2000045 regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q496M5
TrEMBL
UniProt Splice Variant
Entrez Gene 126520
UniGene Hs.195352
RefSeq NM_001243079
HUGO HGNC:27001
OMIM
CCDS CCDS59328
HPRD
IMGT
EMBL AC027307 AK054808 BC100791 DQ424898
GenPept ABD83663 BAG51426
RNA Seq Atlas 126520

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca