Version 5.4
Mus musculus Gene: Osbp
Summary
InnateDB Gene IDBG-147472.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Osbp
Gene Name oxysterol binding protein
Synonyms 1110018F06Rik; AW559088; mKIAA4220
Species Mus musculus
Ensembl Gene ENSMUSG00000024687
Encoded Proteins
IDBP-147474
oxysterol binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110048:
Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:11965844-11994105
Strand Forward strand
Band A
Transcripts
ENSMUST00000025590 ENSMUSP00000025590
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
Biological Process
GO:0006869 lipid transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0030054 cell junction
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110048
View Gene Order
ENSBTAG00000020332
Not yet available
Pathways
NETPATH
REACTOME
REACT_198151
Sphingolipid de novo biosynthesis pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3B7Z2
TrEMBL
UniProt Splice Variant
Entrez Gene 76303
UniGene Mm.291279 Mm.472967
RefSeq NM_001033174 XM_006527439
OMIM
CCDS CCDS37925
HPRD
IMGT
MGI ID MGI:97447
MGI Symbol Osbp
EMBL AC124464 AK132663 AK220301 BC094342 BC107327 BC107328
GenPept AAH94342 AAI07328 AAI07329 BAD90226 BAE21289
RNA Seq Atlas 76303

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca