Version 5.4
Homo sapiens Gene: FLRT2
Summary
InnateDB Gene IDBG-14784.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FLRT2
Gene Name fibronectin leucine rich transmembrane protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185070
Encoded Proteins
IDBP-14786
fibronectin leucine rich transmembrane protein 2
IDBP-586698
fibronectin leucine rich transmembrane protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:85530144-85654426
Strand Forward strand
Band q31.3
Transcripts
ENST00000330753 ENSP00000332879
ENST00000556335
ENST00000557419
ENST00000554746 ENSP00000451050
ENST00000555398
ENST00000553627
ENST00000553650
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
GO:0005515 protein binding
GO:0030674 protein binding, bridging
GO:0045499 chemorepellent activity
Biological Process
GO:0007155 cell adhesion
GO:0007411 axon guidance
GO:0008150 biological_process
GO:0035556 intracellular signal transduction
GO:0050919 negative chemotaxis
GO:2001222 regulation of neuron migration
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047414
View Gene Order
ENSBTAG00000021393
Not yet available
Cross-References
SwissProt O43155
TrEMBL B4DM15
UniProt Splice Variant
Entrez Gene 23768
UniGene Hs.533710 Hs.624735 Hs.624765 Hs.634129 Hs.690810 Hs.731808
RefSeq NM_013231 XM_005267489 XM_005267490 XM_006720095
HUGO HGNC:3761
OMIM 604807
CCDS CCDS9877
HPRD
IMGT
EMBL AB007865 AF169676 AK297248 AY358287 BC126249 BC130290 BC143936
GenPept AAF28460 AAI26250 AAI30291 AAI43937 AAQ88654 BAA23701 BAG59727
RNA Seq Atlas 100506718 23768

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca