Mus musculus Gene: Gmpr
Summary
InnateDB Gene IDBG-148099.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gmpr
Gene Name guanosine monophosphate reductase
Synonyms 2310004P21Rik; AV028449
Species Mus musculus
Ensembl Gene ENSMUSG00000000253
Encoded Proteins
guanosine monophosphate reductase
guanosine monophosphate reductase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137198:
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:45507444-45546382
Strand Forward strand
Band A5
Transcripts
ENSMUST00000000260 ENSMUSP00000000260
ENSMUST00000128873 ENSMUSP00000120825
ENSMUST00000129176
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003920 GMP reductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0009117 nucleotide metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005575 cellular_component
GO:1902560 GMP reductase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Purine metabolism pathway
Metabolism pathway
Purine salvage pathway
Metabolism of nucleotides pathway
KEGG
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Purine salvage pathway
Metabolism of nucleotides pathway
Purine metabolism pathway
Metabolism pathway
KEGG
Purine metabolism pathway
INOH
Purine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt Q9DCZ1
TrEMBL F6VY18
UniProt Splice Variant
Entrez Gene 66355
UniGene Mm.290802
RefSeq NM_025508
OMIM
CCDS CCDS26482
HPRD
IMGT
MGI ID MGI:1913605
MGI Symbol Gmpr
EMBL AC154521 AC154817 AK002326 AK084508 BC010827
GenPept AAH10827 BAB22014 BAC39203
RNA Seq Atlas 66355