Version 5.4
| Mus musculus Gene: Mcf2 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-148121.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Mcf2 | ||||||||||
| Gene Name | mcf.2 transforming sequence | ||||||||||
| Synonyms | B230117G22Rik; Dbl; Mcf-2 | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000031139 | ||||||||||
| Encoded Proteins |
mcf.2 transforming sequence
mcf.2 transforming sequence
mcf.2 transforming sequence
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101977:
The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.[provided by RefSeq, Jan 2010] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome X:60055956-60179089 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | A6 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH |
EGFR1 pathway
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| REACTOME |
NRAGE signals death through JNK pathway
G alpha (12/13) signalling events pathway
Rho GTPase cycle pathway
Signalling by NGF pathway
Signaling by Rho GTPases pathway
Signaling by GPCR pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
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| KEGG | |||||||||||
| INOH |
Integrin signaling pathway pathway
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| PID NCI |
Regulation of RAC1 activity
Regulation of RhoA activity
Regulation of CDC42 activity
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| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | |||||||||||
| UniGene | Mm.93796 | ||||||||||
| RefSeq | NM_001289730 NM_001289731 NM_133197 XM_006527742 XM_006527746 XM_006527747 XM_006527748 XM_006527749 XM_006527750 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS30160 CCDS72384 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | |||||||||||
| MGI Symbol | |||||||||||
| EMBL | |||||||||||
| GenPept | |||||||||||
| RNA Seq Atlas | |||||||||||