Version 5.4
Mus musculus Gene: Npw
Summary
InnateDB Gene IDBG-148506.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Npw
Gene Name neuropeptide W
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000071230
Encoded Proteins
IDBP-148508
neuropeptide W
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Orthologs of this gene express a preproprotein that is processed into a neuropeptide ligand for two G-protein coupled receptors in the central nervous system. The neuropeptide is thought to directly or indirectly regulate feeding, weight regulation, and pain response. The preproprotein is translated using a non-AUG initiation codon. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:24657330-24658457
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000095544 ENSMUSP00000093200
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001664 G-protein coupled receptor binding
GO:0005515 protein binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007631 feeding behavior
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000183971
View Gene Order
ENSBTAG00000046703
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F7B5D6 Q3V2F0
UniProt Splice Variant
Entrez Gene 381073
UniGene Mm.291772
RefSeq NM_001099664
OMIM
CCDS CCDS50017
HPRD
IMGT
MGI ID MGI:2685781
MGI Symbol Npw
EMBL AC154566 AK131881
GenPept BAE20848
RNA Seq Atlas 381073

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca