Version 5.4
Mus musculus Gene: Ddx25
Summary
InnateDB Gene IDBG-148666.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx25
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
Synonyms AW047046; GRTH
Species Mus musculus
Ensembl Gene ENSMUSG00000032101
Encoded Proteins
IDBP-148668
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109832:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein is a gonadotropin-regulated and developmentally expressed testicular RNA helicase. It may serve to maintain testicular functions related to steroidogenesis and spermatogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:35541847-35558528
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000034612 ENSMUSP00000034612
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004004 ATP-dependent RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006406 mRNA export from nucleus
GO:0006417 regulation of translation
GO:0007275 multicellular organismal development
GO:0007286 spermatid development
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0033391 chromatoid body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000109832
View Gene Order
ENSBTAG00000004266
Not yet available
Cross-References
SwissProt Q9QY15
TrEMBL
UniProt Splice Variant
Entrez Gene 30959
UniGene Mm.291723 Mm.467910
RefSeq NM_013932
OMIM
CCDS CCDS52753
HPRD
IMGT
MGI ID MGI:1353582
MGI Symbol Ddx25
EMBL AF142630 AK050693 AK078340 AY380080 AY380081 AY380082 AY380083 AY380084 AY380085 AY380086 AY380087 AY380088 AY380089 AY380090 AY380091 BC024852 BC061130
GenPept AAF21361 AAH24852 AAH61130 AAR26239 BAC34384 BAC37227
RNA Seq Atlas 30959

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca