Version 5.4
Homo sapiens Gene: RXFP3
Summary
InnateDB Gene IDBG-14870.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RXFP3
Gene Name relaxin/insulin-like family peptide receptor 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182631
Encoded Proteins
IDBP-14872
relaxin/insulin-like family peptide receptor 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:33936386-33938237
Strand Forward strand
Band p13.2
Transcripts
ENST00000330120 ENSP00000328708
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008528 G-protein coupled peptide receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0032467 positive regulation of cytokinesis
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060735
View Gene Order
ENSBTAG00000039929
Not yet available
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_21314
Relaxin receptors pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9NSD7
TrEMBL
UniProt Splice Variant
Entrez Gene 51289
UniGene Hs.170146
RefSeq NM_016568
HUGO HGNC:24883
OMIM 609445
CCDS CCDS3900
HPRD
IMGT
EMBL AY236541 AY394501 BC113438 BC113440 D88437
GenPept AAI13439 AAI13441 AAO92063 AAQ92315 BAA93001
RNA Seq Atlas 51289

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca