Version 5.4
Mus musculus Gene: Tiparp
Summary
InnateDB Gene IDBG-149381.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tiparp
Gene Name TCDD-inducible poly(ADP-ribose) polymerase
Synonyms ARTD14; AW558171; PARP7
Species Mus musculus
Ensembl Gene ENSMUSG00000034640
Encoded Proteins
IDBP-149383
TCDD-inducible poly(ADP-ribose) polymerase
IDBP-540943
TCDD-inducible poly(ADP-ribose) polymerase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163659:
This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:65528410-65555145
Strand Forward strand
Band E1
Transcripts
ENSMUST00000047906 ENSMUSP00000048051
ENSMUST00000130705 ENSMUSP00000119951
ENSMUST00000154094
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0035326 enhancer binding
GO:0046872 metal ion binding
Biological Process
GO:0001570 vasculogenesis
GO:0001822 kidney development
GO:0006471 protein ADP-ribosylation
GO:0006807 nitrogen compound metabolic process
GO:0008209 androgen metabolic process
GO:0008210 estrogen metabolic process
GO:0008585 female gonad development
GO:0009791 post-embryonic development
GO:0010629 negative regulation of gene expression
GO:0030097 hemopoiesis
GO:0044236 multicellular organismal metabolic process
GO:0045732 positive regulation of protein catabolic process
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048705 skeletal system morphogenesis
GO:0048745 smooth muscle tissue development
GO:0060021 palate development
GO:0060325 face morphogenesis
GO:0071407 cellular response to organic cyclic compound
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163659
View Gene Order
ENSBTAG00000012120
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.246398 Mm.481406
RefSeq NM_178892
OMIM
CCDS CCDS17388
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca