Mus musculus Gene: Ggct | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-149409.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Ggct | ||||||
Gene Name | gamma-glutamyl cyclotransferase | ||||||
Synonyms | A030007L17Rik; AA673177; Gctg; Ggc | ||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000002797 | ||||||
Encoded Proteins |
gamma-glutamyl cyclotransferase
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006625:
The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 6:54982580-54992950 | ||||||
Strand | Reverse strand | ||||||
Band | B3 | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||
NETPATH | |||||||
REACTOME |
Phase II conjugation pathway
Metabolism pathway
Glutathione conjugation pathway
Glutathione synthesis and recycling pathway
Biological oxidations pathway
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KEGG |
Glutathione metabolism pathway
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INOH | |||||||
PID NCI | |||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Glutathione synthesis and recycling pathway
Glutathione conjugation pathway
Phase II conjugation pathway
Metabolism pathway
Biological oxidations pathway
Glutathione conjugation pathway
Biological oxidations pathway
Glutathione synthesis and recycling pathway
Metabolism pathway
Phase II conjugation pathway
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KEGG |
Glutathione metabolism pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | |||||||
UniGene | Mm.294708 | ||||||
RefSeq | NM_026637 | ||||||
OMIM | |||||||
CCDS | CCDS20161 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | |||||||
MGI Symbol | |||||||
EMBL | |||||||
GenPept | |||||||
RNA Seq Atlas | |||||||