Mus musculus Gene: Tusc3
Summary
InnateDB Gene IDBG-149490.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tusc3
Gene Name tumor suppressor candidate 3
Synonyms AU022242; BC003311; N33
Species Mus musculus
Ensembl Gene ENSMUSG00000039530
Encoded Proteins
tumor suppressor candidate 3
tumor suppressor candidate 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104723:
This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:39005867-39165112
Strand Forward strand
Band A4
Transcripts
ENSMUST00000167992 ENSMUSP00000126080
ENSMUST00000169034 ENSMUSP00000129916
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0015095 magnesium ion transmembrane transporter activity
Biological Process
GO:0015693 magnesium ion transport
GO:0018279 protein N-linked glycosylation via asparagine
GO:0045454 cell redox homeostasis
GO:0050890 cognition
Cellular Component
GO:0005739 mitochondrion
GO:0008250 oligosaccharyltransferase complex
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
N-Glycan biosynthesis pathway
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
KEGG
N-Glycan biosynthesis pathway
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q99J74
UniProt Splice Variant
Entrez Gene 80286
UniGene Mm.272722
RefSeq NM_030254
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:1933134
MGI Symbol Tusc3
EMBL AC168314 AC174643 BC003311 CAAA01027656
GenPept AAH03311
RNA Seq Atlas 80286