Mus musculus Protein: Tusc3
Summary
InnateDB Protein IDBP-627558.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tusc3
Protein Name tumor suppressor candidate 3
Synonyms AU022242; BC003311; N33;
Species Mus musculus
Ensembl Protein ENSMUSP00000126080
InnateDB Gene IDBG-149490 (Tusc3)
Protein Structure
UniProt Annotation
Function Magnesium transporter. May be involved in N- glycosylation through its association with N-oligosaccharyl transferase (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0015095 magnesium ion transmembrane transporter activity
Biological Process
GO:0015693 magnesium ion transport
GO:0018279 protein N-linked glycosylation via asparagine
GO:0045454 cell redox homeostasis
GO:0050890 cognition
Cellular Component
GO:0005739 mitochondrion
GO:0008250 oligosaccharyltransferase complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1933134
InterPro IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain
IPR021149 Oligosaccharyl transferase complex, subunit OST3/OST6
PFAM PF13098
PF13192
PF13462
PF13905
PF00085
PF04756
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BTV1
PhosphoSite PhosphoSite-Q8BTV1
TrEMBL
UniProt Splice Variant
Entrez Gene 80286
UniGene Mm.272722
RefSeq NP_084530
MGI ID
MGI Symbol Tusc3
OMIM
CCDS
HPRD
IMGT
EMBL AC168314 AC174643 AK088616 AK132766 BC069898 CAAA01027656
GenPept AAH69898 BAC40455 BAE21346