Version 5.4
| Mus musculus Gene: Ptx4 | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-150759.6 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | Ptx4 | ||||
| Gene Name | pentraxin 4 | ||||
| Synonyms | 1110018H23Rik | ||||
| Species | Mus musculus | ||||
| Ensembl Gene | ENSMUSG00000044172 | ||||
| Encoded Proteins |
pentraxin 4
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| Protein Structure | |||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000251692:
PTX4 belongs to the pentraxin (PTX) superfamily of multifunctional conserved proteins. Pentraxins are characterized by a cyclic multimeric structure and a conserved C-terminal pentraxin domain of approximately 200 amino acids. All pentraxins have a conserved 8-amino acid sequence, HxCxS/TWxS, in which x is any amino acid, within their pentraxin domain. Pentraxins are divided into short proteins, such as C-reactive protein (CRP; MIM 123260) and serum amyloid P protein (APCS; MIM 104770), and long proteins, such as PTX3 (MIM 602492) and PTX4. Some PTXs are part of the humoral arm of innate immunity and behave as functional ancestors of antibodies by mediating agglutination, complement activation, and opsonization (summary by Martinez de la Torre et al., 2010 [PubMed 20357257]).[supplied by OMIM, Jun 2010] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 17:25120760-25125268 | ||||
| Strand | Forward strand | ||||
| Band | A3.3 | ||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||
| SwissProt | |||||
| TrEMBL | E9QNW3 | ||||
| UniProt Splice Variant | |||||
| Entrez Gene | 68509 | ||||
| UniGene | Mm.328855 | ||||
| RefSeq | NM_001163416 NM_026747 XM_006524846 | ||||
| OMIM | |||||
| CCDS | CCDS50031 | ||||
| HPRD | |||||
| IMGT | |||||
| MGI ID | MGI:1915759 | ||||
| MGI Symbol | Ptx4 | ||||
| EMBL | AC130711 | ||||
| GenPept | |||||
| RNA Seq Atlas | 68509 | ||||