Version 5.4
| Homo sapiens Gene: PTX4 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-402293.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | PTX4 | ||||||
| Gene Name | pentraxin 4, long | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Gene | ENSG00000251692 | ||||||
| Encoded Proteins |
pentraxin 4, long
pentraxin 4, long
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
PTX4 belongs to the pentraxin (PTX) superfamily of multifunctional conserved proteins. Pentraxins are characterized by a cyclic multimeric structure and a conserved C-terminal pentraxin domain of approximately 200 amino acids. All pentraxins have a conserved 8-amino acid sequence, HxCxS/TWxS, in which x is any amino acid, within their pentraxin domain. Pentraxins are divided into short proteins, such as C-reactive protein (CRP; MIM 123260) and serum amyloid P protein (APCS; MIM 104770), and long proteins, such as PTX3 (MIM 602492) and PTX4. Some PTXs are part of the humoral arm of innate immunity and behave as functional ancestors of antibodies by mediating agglutination, complement activation, and opsonization (summary by Martinez de la Torre et al., 2010 [PubMed 20357257]).[supplied by OMIM, Jun 2010] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 16:1485886-1488981 | ||||||
| Strand | Reverse strand | ||||||
| Band | p13.3 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||
| SwissProt | Q96A99 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 390667 | ||||||
| UniGene | Hs.553770 | ||||||
| RefSeq | NM_001013658 | ||||||
| HUGO | HGNC:14171 | ||||||
| OMIM | 613442 | ||||||
| CCDS | CCDS32362 | ||||||
| HPRD | 18401 | ||||||
| IMGT | |||||||
| EMBL | AE006467 AL031705 BC156066 BC156944 CH471112 | ||||||
| GenPept | AAI56067 AAI56945 AAK61283 EAW85652 | ||||||
| RNA Seq Atlas | 390667 | ||||||