InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Col5a2

Summary

InnateDB Gene

IDBG-150868.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col5a2

Gene Name

collagen, type V, alpha 2

Synonyms

1110014L14Rik; D230017N05

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026042

Encoded Proteins

IDBP-150870

collagen, type V, alpha 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204262:
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:45374321-45503282

Strand

Reverse strand

Band

C1.1

Transcripts

ENSMUST00000086430	ENSMUSP00000083620
ENSMUST00000150143
ENSMUST00000134681
ENSMUST00000131535

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005201	extracellular matrix structural constituent
GO:0005515	protein binding
GO:0046332	SMAD binding
GO:0046872	metal ion binding

Biological Process

GO:0001501	skeletal system development
GO:0001503	ossification
GO:0030199	collagen fibril organization
GO:0043588	skin development
GO:0048592	eye morphogenesis
GO:0071230	cellular response to amino acid stimulus