Homo sapiens Gene: COL5A2 | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-77225.6 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | COL5A2 | ||||||||||||||||||||
Gene Name | collagen, type V, alpha 2 | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||
Ensembl Gene | ENSG00000204262 | ||||||||||||||||||||
Encoded Proteins |
collagen, type V, alpha 2
collagen, type V, alpha 2
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 2:189031896-189179879 | ||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||
Band | q32.2 | ||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
Integrin cell surface interactions pathway
Signaling by PDGF pathway
Assembly of collagen fibrils and other multimeric structures pathway
Collagen biosynthesis and modifying enzymes pathway
Collagen degradation pathway
NCAM1 interactions pathway
NCAM signaling for neurite out-growth pathway
Developmental Biology pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
Syndecan interactions pathway
Axon guidance pathway
Signal Transduction pathway
ECM proteoglycans pathway
Non-integrin membrane-ECM interactions pathway
Collagen formation pathway
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KEGG |
ECM-receptor interaction pathway
Focal adhesion pathway
Amoebiasis pathway
Protein digestion and absorption pathway
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INOH |
Integrin signaling pathway pathway
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PID NCI |
Beta1 integrin cell surface interactions
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Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | D3DPH5 | ||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | 1290 | ||||||||||||||||||||
UniGene | |||||||||||||||||||||
RefSeq | NM_000393 | ||||||||||||||||||||
HUGO | HGNC:2210 | ||||||||||||||||||||
OMIM | 120190 | ||||||||||||||||||||
CCDS | CCDS33350 | ||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | CH471058 | ||||||||||||||||||||
GenPept | EAX10907 EAX10908 | ||||||||||||||||||||
RNA Seq Atlas | 1290 | ||||||||||||||||||||