Version 5.4
Mus musculus Gene: Nmrk1
Summary
InnateDB Gene IDBG-151212.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nmrk1
Gene Name nicotinamide riboside kinase 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037847
Encoded Proteins
IDBP-151214
cDNA sequence BC016495
IDBP-538110
cDNA sequence BC016495
IDBP-532473
cDNA sequence BC016495
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106733:
Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 [PubMed 15137942]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:18631950-18652194
Strand Forward strand
Band B
Transcripts
ENSMUST00000042392 ENSMUSP00000037198
ENSMUST00000159061
ENSMUST00000159572 ENSMUSP00000125384
ENSMUST00000161080 ENSMUSP00000125565
ENSMUST00000162446
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0050262 ribosylnicotinamide kinase activity
Biological Process
GO:0008150 biological_process
GO:0009435 NAD biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000106733
View Gene Order
ENSBTAG00000019687
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00760
Nicotinate and nicotinamide metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00760
Nicotinate and nicotinamide metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.412740
RefSeq NM_145497
OMIM
CCDS CCDS37931
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca