Homo sapiens Gene: NMRK1
Summary
InnateDB Gene IDBG-71621.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NMRK1
Gene Name nicotinamide riboside kinase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106733
Encoded Proteins
chromosome 9 open reading frame 95
chromosome 9 open reading frame 95
chromosome 9 open reading frame 95
chromosome 9 open reading frame 95
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 [PubMed 15137942]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:75060573-75088217
Strand Reverse strand
Band q21.13
Transcripts
ENST00000376811 ENSP00000366007
ENST00000361092 ENSP00000354387
ENST00000376808 ENSP00000366004
ENST00000482537
ENST00000494066 ENSP00000435736
ENST00000466137
ENST00000490321
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
GO:0050262 ribosylnicotinamide kinase activity
Biological Process
GO:0009435 NAD biosynthetic process
GO:0016310 phosphorylation
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Nicotinate and nicotinamide metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.494186 Hs.604219 Hs.610743
RefSeq NM_001127603 NM_017881 XM_006717163 XM_006717165
HUGO
OMIM
CCDS CCDS47981 CCDS6650
HPRD 09868
IMGT
EMBL
GenPept
RNA Seq Atlas