Version 5.4
Mus musculus Gene: Ppm1k
Summary
InnateDB Gene IDBG-151294.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppm1k
Gene Name protein phosphatase 1K (PP2C domain containing)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037826
Encoded Proteins
IDBP-151296
protein phosphatase 1K (PP2C domain containing)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163644:
This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:57506502-57535426
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000042766 ENSMUSP00000041395
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006470 protein dephosphorylation
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163644
View Gene Order
ENSBTAG00000005754
Not yet available
Cross-References
SwissProt Q8BXN7
TrEMBL B9EHW0
UniProt Splice Variant
Entrez Gene 243382
UniGene Mm.396893 Mm.489618
RefSeq NM_175523
OMIM
CCDS CCDS20183
HPRD
IMGT
MGI ID MGI:2442111
MGI Symbol Ppm1k
EMBL AK044610 BC092238 BC138473 BC138474 CH466643
GenPept AAH92238 AAI38474 AAI38475 BAC32001 EDL04740
RNA Seq Atlas 243382

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca