Version 5.4
Mus musculus Gene: Frg1
Summary
InnateDB Gene IDBG-151308.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Frg1
Gene Name FSHD region gene 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031590
Encoded Proteins
IDBP-151310
FSHD region gene 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109536:
This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:41397457-41417118
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000033999 ENSMUSP00000033999
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030674 protein binding, bridging
GO:0044822 poly(A) RNA binding
GO:0051015 actin filament binding
Biological Process
GO:0006364 rRNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0015030 Cajal body
GO:0016607 nuclear speck
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000109536
View Gene Order
ENSBTAG00000007089
Not yet available
Cross-References
SwissProt P97376
TrEMBL Q78P92
UniProt Splice Variant
Entrez Gene 14300
UniGene
RefSeq NM_013522
OMIM
CCDS CCDS22263
HPRD
IMGT
MGI ID MGI:893597
MGI Symbol Frg1
EMBL AK077107 AK079229 AY028080 BC002027 CH466554 U62105
GenPept AAB39540 AAH02027 AAK21978 BAC36616 BAC37582 EDL35522
RNA Seq Atlas 14300

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca