Mus musculus Gene: Ywhah | |||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||
InnateDB Gene | IDBG-152570.6 | ||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||
Gene Symbol | Ywhah | ||||||||||||||||||||||||
Gene Name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | ||||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000018965 | ||||||||||||||||||||||||
Encoded Proteins |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
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Protein Structure | |||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128245:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009] This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99%% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5\' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009] |
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Gene Information | |||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||
Genomic Location | Chromosome 5:33018816-33027966 | ||||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||||
Band | B1 | ||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 113 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||
REACTOME |
Apoptosis pathway
Membrane Trafficking pathway
Activation of BAD and translocation to mitochondria pathway
Activation of BH3-only proteins pathway
Translocation of GLUT4 to the plasma membrane pathway
Intrinsic Pathway for Apoptosis pathway
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KEGG |
Cell cycle pathway
Oocyte meiosis pathway
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INOH | |||||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||
NETPATH |
Alpha6Beta4Integrin pathway
TNFalpha pathway
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REACTOME |
Activation of BAD and translocation to mitochondria pathway
Translocation of GLUT4 to the plasma membrane pathway
Apoptosis pathway
Activation of BH3-only proteins pathway
Intrinsic Pathway for Apoptosis pathway
Membrane Trafficking pathway
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KEGG |
Cell cycle pathway
Oocyte meiosis pathway
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INOH |
Wnt signaling pathway pathway
Insulin receptor signaling pathway
Fas signaling pathway pathway
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PID NCI |
Glucocorticoid receptor regulatory network
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Cross-References | |||||||||||||||||||||||||
SwissProt | P68510 | ||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||
Entrez Gene | 22629 | ||||||||||||||||||||||||
UniGene | Mm.332314 Mm.354610 Mm.400013 | ||||||||||||||||||||||||
RefSeq | NM_011738 | ||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||
CCDS | CCDS19198 | ||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||
MGI ID | MGI:109194 | ||||||||||||||||||||||||
MGI Symbol | Ywhah | ||||||||||||||||||||||||
EMBL | AB063572 AF077002 AK077596 AK149224 AK168520 AK169035 AK169189 BC008187 BC061497 D87661 U57311 | ||||||||||||||||||||||||
GenPept | AAC36290 AAC53256 AAH08187 AAH61497 BAA13422 BAB79599 BAC36887 BAE28768 BAE40399 BAE40826 BAE40965 | ||||||||||||||||||||||||
RNA Seq Atlas | 22629 | ||||||||||||||||||||||||