InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc5a1

Summary

InnateDB Gene

IDBG-152618.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc5a1

Gene Name

solute carrier family 5 (sodium/glucose cotransporter), member 1

Synonyms

Sglt1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000011034

Encoded Proteins

IDBP-152620

solute carrier family 5 (sodium/glucose cotransporter), member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100170:
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:33104219-33162872

Strand

Forward strand

Band

Transcripts

ENSMUST00000011178

ENSMUSP00000011178

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005355	glucose transmembrane transporter activity
GO:0005412	glucose:sodium symporter activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0015758	glucose transport
GO:0050892	intestinal absorption
GO:0055085	transmembrane transport

Cellular Component

GO:0005903	brush border
GO:0005911	cell-cell junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0031526	brush border membrane
GO:0070062	extracellular vesicular exosome